About the position
The Department of Molecular and Cell Biology at the University of California, Berkeley seeks applications for an Assistant/Associate Specialist in the Mevissen Lab, in the area of transcription-coupled DNA repair and genome maintenance. The Mevissen Lab studies the molecular mechanisms that coordinate transcription with DNA repair and genome maintenance. A major goal of the lab is to understand how cells detect DNA damage that interferes with transcription and how repair factors, RNA polymerase II, chromatin-associated proteins, and other factors cooperate to resolve these lesions. The successful candidate will contribute to projects using biochemical, molecular biology, and cell-free experimental approaches, including Xenopus egg extract systems, to investigate transcription-coupled DNA repair and related genome maintenance pathways. The position will also include research-support responsibilities that directly support the lab’s scientific goals. Applicants must be authorized to work in the United States at the time of hire. Visa sponsorship is not available for this position. Responsibilities: Under the general direction of the laboratory head, the Assistant/Associate Specialist will work closely with other members of the Mevissen Lab while providing independent input on the design, execution, optimization, and troubleshooting of experiments within the lab’s research program. The position will focus on establishing and applying biochemical, molecular biology, and cell-free experimental approaches, including Xenopus egg extract-based systems, to study transcription-coupled DNA repair and related genome maintenance pathways. The position will contribute to the lab’s research program in several major ways: 1) designing, performing, optimizing, and troubleshooting biochemical and molecular biology experiments related to transcription-coupled DNA repair; 2) preparing, using, and helping establish cell-free biochemical systems, including Xenopus egg extract-based assays and related experimental workflows; 3) analyzing experimental results, maintaining detailed records, documenting protocols, and communicating findings through lab meetings, presentations, manuscripts, and other research outputs; and 4) supporting research operations that directly advance the lab’s scientific goals, including laboratory organization, reagent and inventory management, safety/compliance documentation, and training junior lab members in specialized experimental techniques.
Qualifications
Basic qualifications (required at time of application) Bachelor’s degree (or equivalent international degree) Additional qualifications (required at time of start) A minimum of three years of research experience after completion of a bachelor’s degree (or equivalent international degree) Preferred qualifications Bachelor’s degree (or equivalent international degree) in Biology, Biochemistry, Molecular Biology, Genetics, Cell Biology, Biophysics, or a related field, with at least 3 years of hands-on laboratory research experience Master’s degree (or equivalent international degree) in Biology, Biochemistry, Molecular Biology, Genetics, Cell Biology, Biophysics, or a related field, with at least 1 year of hands-on laboratory research experience Experience with mechanistic studies of DNA repair, transcription, DNA replication, protein-nucleic acid interactions, or related areas Experience with cell-free biochemical systems, biochemical reconstitution, or Xenopus egg extract systems Experience designing, performing, optimizing, and troubleshooting biochemical or molecular biology assays Experience analyzing, documenting, and communicating experimental results Demonstrated contributions to peer-reviewed publications or other scientific outputs Experience training or mentoring junior researchers in specialized laboratory techniques Experience supporting research operations, such as laboratory organization, inventory management, safety/compliance documentation, or standard operating procedure development
How to apply
Document requirements Cover Letter Curriculum Vitae - Your most recently updated C.V. Reference requirements 3 required (contact information only) Apply link: https://aprecruit.berkeley.edu/JPF05526 Help contact: mevissen@berkeley.edu
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