About the position
## PhD Research Fellow in Bioinformatics and Computational Biology Epigen ## More about the position The project aims to develop novel computational methods and tools for predicting functional non-coding mutations in the cancer genome. These methods will integrate diverse sources of information, including the biophysical principles of protein–DNA interactions, the genetic and epigenetic features of DNA sequences, and the three-dimensional (3D) organization of the genome and its regulatory landscape. A particular focus will be on integrating multi-omics data generated from single-cell experiments to improve both predictive accuracy and biological interpretability. The PhD research fellow will primarily focus on developing data mining methods such as network analysis in 3D genome regulation that integrate diverse biological information, including transcription factor (TF)–DNA interactions, epigenetic features, and 3D genome organization, to identify functional non-coding mutations and their targets in long-distance regions. Subsequently, the predictions will be validated in cancer by using both in vivo and in vitro experimental data. Depending on the candidate's qualifications and the progress of the project, there may be an opportunity to undertake a 3–6-month research visit to the laboratory of one of our international collaborators in the United States. This visit will provide advanced training in computational approaches for studying single-cell 3D genome regulation and further strengthen the international collaboration. ## We offer - Exciting and meaningfultasks in an organization with an important societal mission, contributing toknowledge development, education, andenlightenment that promote sustainable, fair, andknowledge-based societal development. - Committed colleagues in a good working environment. A pleasantand stimulatingwork environment. - Good welfare schemes. - Opportunity of up to 1.5hours a week of exercise during working hours. A workplace with good development and careeropportunities. - Membership in the Statens Pensjonskasse, which is one of Norway's best pension schemes,with beneficialmortgages and good insurance schemes. - Salary in the position as DoctoralResearch Fellow, position code1017 in the salary range of NOK 550 800 -600 000, depending oncompetence and experience. From the salary, 2 percent isdeducted in statutory contributions to theState Pension Fund. - Read more about the benefitsof working in thepublic sector at Employer Portal. ## Application Your application should include: - Application cover letter (statement of motivation and research interests) - CV (summarizing education, positions and academic work - scientific publications) - A copy of the Master's thesis, a list of publications and academic works (maximum 5) that you wish to be considered by the committee - Certified copies of the original Bachelor and Master's degree diploma and the transcripts of records - Documentation of English proficiency if applicable - Contact information for at least 3 references (name, relation to the candidate, institutional email address and telephone number) Your CV must be entered in Jobbnorge’s CV form and cannot be submitted only as an attachment. This requirement is intended to ensure correct documentation and record-keeping in accordance with the Public Administration Act, Section 15. Application with attachments must be submitted via our recruitment system Jobbnorge, click "Apply for this job". When applying for the position, we ask you to retrieve your education results from Vitnemålsportalen.no. If your education results are not available through Vitnemålsportalen, we ask you to upload copies of your transcripts or grades. Please note that all documentation must be in English or a Scandinavian language.
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