Postdoc Position in Medicinal Chemistry

Postdoc Position in Medicinal Chemistry
Utrecht University - Faculty of Science
Utrecht, Netherlands
€ 3.706 - € 5.760 per month gross
Your job
As a postdoc, you will play a key role in the discovery and development of novel Piezo1 inhibitors for sickle cell disease, combining virtual screening, AI-techniques and organic synthesis. Initial inhibitors have already been identified, providing a starting point for further optimization and broader screening. You will work closely with researchers at UMC Utrecht where compounds will be assayed. The project combines fundamental research with translational potential and offers opportunities to interact with experts in the field through periodic user committee meetings.
You will work in the Chemical Biology and Drug Discovery division of the Utrecht Institute of Pharmaceutical Sciences. The division houses around 60 researchers with expertise in preparative chemistry linked to disease research, carbohydrates and glycoscience, RNA in disease, immunology and drug discovery.
You will have access to modern synthetic labs, state of the art analytical equipment, biolabs and large scale computation facilities. Regular in person meetings with our partner group at the UMC will support the close collaboration on this project. Our goal is to advance successful compounds in subsequent translational activities.
As a postdoctoral researcher, you will have the opportunity to develop your expertise across synthetic and computational medicinal chemistry and apply modern approaches to compound discovery and optimization.
Your qualities
We are looking for an enthusiastic scientist with:
a completed PhD in Medicinal Chemistry;
experience in organic synthesis of drug-like compounds;
experience in molecular modelling/docking experience in the creation and development of bioactive compounds;
proficiency in written and spoken English.
Apply Now
Deadline 18 November
Don't forget to mention EuroScienceJobs when applying.
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Postdoc
Utrecht University - Faculty of Science