Postdoctoral Fellow in Molecular Cell Biology

University of Oslo Institutt for klinisk medisin (Klinmed) Oslo, Norway

About the position

## Project description Most cancer cells exhibit persistent endoplasmic reticulum stress, which promotes tumour growth, metastasis and resistance to therapies. Stressed endoplasmic reticulum is cleared by a pathway known as "ER-phagy", yet it remains unclear how ER-phagy dysregulation contributes to cancer progression. Using image-based siRNA screens, we have identified novel regulators of ER-phagy. This project aims to investigate the molecular mechanisms of ER-phagy and how this contributes to cancer progression. The successful candidate should have extensive experience from experimental laboratory work in molecular cell biology using techniques such as cell culture, CRISPR/Cas9 based genome editing, protein expression and interaction analysis, light microscopy and/or cancer assays. Prior experience in the autophagy or intracellular trafficking fields is considered an advantage. We are looking for a highly motivated individual with the ability to work in an accurate and structured manner to carry out the project within the given timeframe. The candidate should be able to work both independently and collaboratively, and be able to effectively interpret and communicate research results. The candidate may also have the opportunity to supervise students. ## We offer - Exciting and meaningful tasks in an organization with an important societal mission, contributing to knowledge development, education, and enlightenment that promote sustainable, fair, and knowledge-based societal development. - A pleasant and stimulating work environment - Good welfare schemes. - Opportunity of up to 1.5 hours a week of exercise during working hours. - A workplace with good development and career opportunities. - Membership in the Statens Pensjonskasse, which is one of Norway's best pension schemes with beneficial mortgages and good insurance schemes. - Salary in position as Postdoctoral Fellow, position code 1352 in salary range NOK from 595 000 to 680 000, depending on competence and experience. From the salary, 2 percent is deducted in statutory contributions to the State Pension Fund. Read more about the benefits of working in the public sector at Employer Portal. ## Application Your application should include: - Application letter - CV - A complete list of publications - Project description - Transcripts and certificates - Contact information for 2-3 references Your CV must be entered in Jobbnorge’s CV form and cannot be submitted only as an attachment. This requirement is intended to ensure correct documentation and record-keeping in accordance with the Public Administration Act, Section 15. Application with attachments must be submitted via our recruitment system Jobbnorge, click "Apply for this job". When applying for the position, we ask you to retrieve your education results from Vitnemålsportalen.no. If your education results are not available through Vitnemålsportalen, we ask you to upload copies of your transcripts or grades. Please note that all documentation must be in English or a Scandinavian language.

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