About the position
## UiB - Knowledge that shapes society UiB shall be among Europe's leading universities, internationally recognized for high quality in research and education. As a societal institution, we shall contribute to sustainable and democratic development and be an attractive and inclusive place to study and work. ## Postdoctoral Research Fellow position The Faculty of Medicine, Department of Biomedicine, invites applications for a full-time position as a Postdoctoral Research Fellow for a period of three(3) years. Subject to the availability of additional funding, the appointment may be extended to four (4) years. The position is part of the project ” eHACS”, financed by the Research Council of Norway. The successful candidate will join the eHACS project, and contribute to the experimental evaluation of the designed compounds for activity against their targets (FabF, PanK, and NMT) and to determine crystal structures of protein-ligand complexes to inform compound design. The postdoc will be part of the Brenk lab which conducts research in the area of structure-based drug design. ## About the project/work tasks: - Protein expression and purification - Determination of ligand binding using label-free biophysical methods - Determination of enzyme activities using biochemical methods - Determination of crystal structures of target-ligand complexes - Analysis of target-ligand structures to inform compound design ## Qualifications and personal qualities: - The applicant must hold a Norwegian PhD or an equivalent degree within structural biology or have the doctoral thesis submitted prior to the application deadline. It is a condition of employment that the PhD has been awarded at the latest within 5 months after the closing date for applications. - Experience with using label-free biophysical methods (e.g. BLI, SPR, or GCI) to determine binding of small molecules to proteins is required. - Experience with structure determination of protein-ligand complexes in a structure-based drug design context is required - Experience with protein expression and purification of at least one of the target proteins (FabF, PanK or NMT) is required. - The successful candidate needs to be able to work independently and in a structured manner, and needs to have the ability to cooperate with others - Proficiency in both written and oral English is required. - Experience with biochemical activity assays is an advantage. The applicant’s personal suitability for the position is a significant factor in the evaluation. Special Requirements for the Position The University of Bergen is subjected to the regulations governing the Norwegian export control system. These regulations will be applied in the assessment and processing of the applications. ## We can offer: - Exciting development opportunities as part of your role in a strong professional environment - Salary NOK 690 000 (code 1352) in the state salary scale. (Applicants with specialist training must include a certificate of specialist approval from the Norwegian Directorate of Health). - Enrolment in the Norwegian Public Service Pension Fund - Good welfare benefits ## Your application must include: - A brief account of the applicant`s research interests and motivation for applying for the position - Transcripts and diplomas (applicants with education from other countries than Norway must enclose witnessed diplomas in both the original language and authorized translations) and documentation of submitted doctoral thesis - Complete list of publications - Publications (in PDF) it is important that each of the scholarly works on which the committee should place special emphasis, is attached in its entirety - Two references (name and contact information)
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