Postdoctoral Researcher in Advanced Cell Sorting and Human Tissue Biology

Postdoctoral Researcher in Advanced Cell Sorting and Human Tissue Biology

Do you want to contribute to top quality medical research? We are looking for a highly motivated postdoctoral researcher with strong expertise in fluorescence-activated cell sorting (FACS) and cell isolation from solid tissues to join the research group Chemicals and Female Fertility at Karolinska Institutet. Our research focuses on understanding human ovarian biology, the effects of environmental chemicals on female reproductive health, and development of new in vitro models. We offer an exciting opportunity to develop advanced cell isolation methods using human tissue samples in a multidisciplinary research environment with access to state-of-the-art technologies.

Your mission

The successful candidate will lead the development and optimization of advanced cell isolation and sorting protocols for human ovarian tissue. This includes identifying and validating cell-type-specific markers, designing multicolor FACS panels, and establishing robust methods for isolating viable, well-characterized cell populations from rare human tissue samples. The isolated cells will be used for downstream molecular and functional analyses, as well as cell culture applications, requiring the development of methods to assess cell purity, viability, and functionality. The position also involves experimental data analysis, documentation and communication of results, and active participation in shared research group responsibilities. These include human tissue sample collection and processing, laboratory maintenance and coordination, and administrative duties at the research group, department, and university levels as needed.

Your profile

We are looking for a candidate with solid, demonstrated expertise in FACS of cells isolated from human solid tissues, including tissue dissociation, cell preparation, and sorting. The candidate must have experience in independently developing and optimizing multicolor FACS panels and cell sorting strategies, including marker selection, gating strategies, and assessment of cell purity and viability. Excellent communication skills in English, both written and spoken, and the ability to work independently and collaboratively in a multidisciplinary research environment are required. Experience in establishing and culturing primary human cells, preparation and analysis of omics datasets, and interpretation of omics data are considered meritorious. Knowledge of reproductive biology, particularly ovarian biology, is also an advantage. To be eligible for employment as a postdoctoral researcher, a PhD or a foreign degree deemed to be equivalent to a Swedish PhD is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. Completion of your doctoral degree within the last three years is considered an advantage. If there are special reasons, your degree may have been completed earlier. The duration of the employment is 2 years.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

Tagged as: Life Sciences