Research Specialist A/B

Research Specialist A/B

University Overview

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The University offers a competitive benefits package that includes
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benefits, a wealth of health and wellness programs and resources,
and much more.

Posted Job Title

Research Specialist A/B

Job Profile Title

Research Specialist A

Job Description Summary

The Amado Laboratory, a part of both the Perelman School of
Medicine at the University of Pennsylvania and the Children's
Hospital of Philadelphia, is seeking a highly motivated Research
Specialist A/B to join our research program focused on the
development of gene therapy approaches to treat ALS and related
neurodegenerative disorders.

Job Description

Our lab uses cellular and mouse models of disease to identify
therapeutic targets and develop cutting-edge gene therapy-based
approaches to treat them, including AAV-mediated gene delivery, RNA
interference, gene editing, and ASOs. We are seeking someone who
can help design, conduct, and analyze experiments in immortalized
cell lines, patient-derived stem cells, and mouse models of
diseases of the nervous system in a highly collaborative, fun
environment. The ideal candidate is comfortable with basic existing
lab techniques and is also keen on reading published literature to
identify the most effective, reliable, and novel strategies to
advance the projects' success, and is not afraid to try new things
and troubleshoot. Excellent organization and record-keeping skills
are required. Prior experience with the following techniques is
desired: DNA/RNA/protein extraction, QPCR, western blotting,
molecular cloning, PCR, and cell culture including maintenance and
transfection. Prior experience with mouse handling and knowledge of
or willingness to learn tissue extraction techniques (especially
brain, spinal cord, and/or peripheral nerve) and behavior testing
is preferred, as there is a significant in vivo component to our
work.

Sectioning/immunohistochemistry/immunofluorescence experience is a
bonus, as is experience with imaging acquisition and analysis. For
Research Specialist B applicants, duties will be more autonomous
with a greater level of independence. Further, although both
positions are expected to lead to inclusion in publications from
the lab, a Research Specialist B will also be expected to assist in
generating figures, writing Methods, and other aspects of
manuscript preparation.

Qualifications

• RS-A: Bachelor of Science and 0 to 1 year of experience

or equivalent combination of education and experience is
required.

• Prior experience with mammalian cell culture (including

transfection) and molecular/cell biology is preferred.

• Prior experience working with mice is preferred; openness to it

is required.

• Ability to work both independently and as part of a team are

required.

• Excellent organizational, time management, and critical

thinking skills are required.

• RS-B: Bachelor of Science and 1 to 2 years of experience

or equivalent combination of education and experience is
required.

• Prior experience with mammalian cell culture (including

transfection) and molecular/cell biology is required.

• Prior experience with mice is strongly preferred.

Position is contingent upon continued funding.

Job Location - City, State

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine

Pay Range

$45,278.00 - $60,202.00 Annual Rate

Salary offers are made based on the candidate's qualifications,
experience, skills, and education as they directly relate to the
requirements of the position, and in alignment with salary ranges
based on external market data for the job's level. Internal
organization and peer data at Penn are also considered.

Equal Opportunity Statement

The University of Pennsylvania is an equal opportunity employer.
Candidates are considered for employment without regard to race,
color, sex, sexual orientation, religion, creed, national origin
(including shared ancestry or ethnic characteristics), citizenship
status, age, disability, veteran status or any class protected
under applicable federal, state or local law.

Special Requirements

Background checks may be required after a conditional job offer is
made. Consideration of the background check will be tailored to the
requirements of the job.

University Benefits

• Health, Life, and Flexible Spending Accounts: Penn

offers comprehensive medical, prescription, behavioral health,
dental, vision, and life insurance benefits to protect you and your
family's health and welfare. You can also use flexible spending
accounts to pay for eligible health care and dependent care
expenses with pre-tax dollars.

• Tuition: Take advantage of Penn's exceptional tuition

benefits. You, your spouse, and your dependent children can get
tuition assistance here at Penn. Your dependent children are also
eligible for tuition assistance at other institutions.

• Retirement: Penn offers generous retirement plans to

help you save for your future. Penn's Basic, Matching, and
Supplemental retirement plans allow you to save for retirement on a
pre-tax or Roth basis. Choose from a wide variety of investment
options through TIAA and Vanguard.

• Time Away from Work: Penn provides you with a

substantial amount of time away from work during the course of the
year. This allows you to relax, take vacations, attend to personal
affairs, recover from illness or injury, spend time with
family-whatever your personal needs may be.

• Long-Term Care Insurance: In partnership with Genworth

Financial, Penn offers faculty and staff (and your eligible family
members) long-term care insurance to help you cover some of the
costs of long-term care services received at home, in the community
or in a nursing facility. If you apply when you're newly hired, you
won't have to provide proof of good health or be subject to
underwriting requirements. Eligible family members must always
provide proof of good health and are subject to underwriting.

• Wellness and Work-life Resources: Penn is committed to

supporting our faculty and staff as they balance the competing
demands of work and personal life. That's why we offer a wide
variety of programs and resources to help you care for your health,
your family, and your work-life balance.

• Professional and Personal Development: Penn provides an

array of resources to help you advance yourself personally and
professionally.

• University Resources: As a member of the Penn community,

you have access to a wide range of University resources as well as
cultural and recreational activities. Take advantage of the
University's libraries and athletic facilities, or visit our
arboretum and art galleries. There's always something going on at
Penn, whether it's a new exhibit at the Penn Museum, the latest
music or theater presentation at the Annenberg Center, or the Penn
Relays at Franklin Field to name just a few examples. As a member
of the Penn community, you're right in the middle of the
excitement-and you and your family can enjoy many of these
activities for free.

• Discounts and Special Services: From arts and

entertainment to transportation and mortgages, you'll find great
deals for University faculty and staff. Not only do Penn arts and
cultural centers and museums offer free and discounted admission
and memberships to faculty and staff. You can also enjoy
substantial savings on other goods and services such as new cars
from Ford and General Motors, cellular phone service plans, movie
tickets, and admission to theme parks.

• Flexible Work Hours: Flexible work options offer

creative approaches for completing work while promoting balance
between work and personal commitments. These approaches involve use
of non-traditional work hours, locations, and/or job
structures.

• Penn Home Ownership Services: Penn offers a forgivable

loan for eligible employees interested in buying a home or
currently residing in West Philadelphia, which can be used for
closing costs or home improvements.

• Adoption Assistance: Penn will reimburse eligible

employees on qualified expenses in connection with the legal
adoption of an eligible child, such as travel or court fees, for up
to two adoptions in your household.

To learn more, please visit: https://www.hr.upenn.edu/PennHR/benefits-pay

Equal Employment Opportunity Statement

The University of Pennsylvania is an equal opportunity employer.
Candidates are considered for employment without regard to race,
color, sex, sexual orientation, religion, creed, national origin
(including shared ancestry or ethnic characteristics), citizenship
status, age, disability, veteran status or any class protected
under applicable federal, state, or local law.

To apply, visit https://wd1.myworkdaysite.com/en-US/recruiting/upenn/careers-at-penn/job/CHOP/Research-Specialist-A-B_JR00129023-2

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