Senior Scientist, LC-MS Proteomics

Senior Scientist, LC-MS Proteomics
VIB
Ghent, Belgium
Your Role
You independently operate state-of-the-art high-resolution LC-MS/MS platforms, such as Orbitrap and/or timsTOF instruments, coupled to nanoLC and/or microLC systems;
You develop, optimize, implement and execute LC-MS/MS methods, including LC gradients, MS acquisition parameters and full analytical workflows;
You take ownership of instrument performance and quality control, including tuning, calibration, routine maintenanceand troubleshooting, in order toproactively intervene withperformance deterioration before it impacts research projects;
You carefully document experimental procedures, instrument performance, data and results, and work according to applicable SOPs and quality guidelines;
You contribute to the continuous improvement of existing workflows and to the development and implementation of state-of-the-art LC-MS and proteomics applications;
You stay up-to-date with emerging technologies and developments in LC-MS driven proteomics.

Your qualifications

Essential
BSc, MSc or PhD in analytical chemistry, industrial sciences, biochemistry, biotechnology, biomedical sciences, molecular biology, or a related field;
At least 5 years of relevant hands-on LC-MS/MS experience;
Strong practical experience with high-resolution mass spectrometry platforms, such as Orbitrap and/or timsTOF, coupled to nanoLC and/or microLC systems;
Demonstrated ability to independently operate LC-MS/MS instrumentation, including tuning, calibration, acquisition method setup, routine maintenance, monitor instrument performance and troubleshooting;
Experience in LC-MS/MS method development and optimization, including LC gradients, MS acquisition parameters and complete analytical workflows;
Basic working knowledge of proteomics data analysis and search-engine tools, including protein/peptide identification, quantification, quality control and interpretation.
Desirable
Practical experience with proteomics sample preparation;
Experience with post-translational modification (PTM) analysis;
Experience with multiplexed quantitative proteomics approaches;
Experience with intact protein measurements and characterization;
Experience with targeted proteomics;
Knowledge of statistical analysis and quantitative interpretation of proteomics data;
Experience working in a core facility or service-oriented scientific environment.
Key personal characteristics
Hands-on, proactive and solution-driven;
Strong analytical and problem-solving skills;
Meticulous, organized and committed to delivering reliable, high-quality results;
Scientific curiosity and eagerness to learn and implement new technologies;
Independent team player;
Service-oriented mindset;
Comfortable working in an international setting: fluent in English.
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Don't forget to mention EuroScienceJobs when applying.
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Belgium
Biochemistry
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Biotechnology and Genetics
Chemistry
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VIB