About the position
## UiB - Knowledge that shapes society UiB shall be among Europe's leading universities, internationally recognized for high quality in research and education. As a societal institution, we shall contribute to sustainable and democratic development and be an attractive and inclusive place to study and work. ## Postdoctoral Research Fellow position (3 years), Centre for Cancer Biomarkers (CCBIO), Department of Clinical Medicine At the Faculty of Medicine, Centre for Cancer Biomarkers, Department of Clinical Medicine, a full-time (100 %) position as postdoctoral research fellow is available for a period of three (3) years. The position is part of the project ”Cancer-neuron synapses and behavior of breast cancer”, financed by Norwegian Cancer Society and the Norwegian Breast Cancer Society, Pink Ribbon. ## About the project/work tasks: - This project investigates and maps functional interactions between peripheral nerves and breast cancer cells by combining advanced tissue studies with experimental cell models. - The postdoctoral researcher will work with human co-culture models based on stem cell-derived neurons and breast cancer organoids, together with clinical tissue material, to investigate cancer-nerve contact sites using multiplexed immunofluorescence, single-cell and single-nucleus transcriptomics and proteomic profiling. ## Qualifications and personal qualities: - The applicant must hold a Norwegian PhD or an equivalent degree within neurobiology/ tumor biology, or equivalent in a relevant field of research or have the doctoral thesis submitted prior to the application deadline. It is a condition of employment that the PhD has been awarded at the latest within 5 months after the closing date for applications. - Documented hands-on experience with isolation, quality assessment and preparation of single-cell and/or nuclei suspensions from complex biological material for downstream single-cell or single-nucleus transcriptomics profiling is required. - Practical experience generating single-cell or single-nucleus RNA-sequencing data using 10x Genomics or equivalent platforms, including sample quality control and library preparation is required. - The applicant must have strong independent bioinformatics and programming skills in R, Python or equivalent. The applicant must be able to perform end-to-end analysis of single-cell and/or single-nucleus RNA-sequencing datasets. This includes quality control, normalization, dimensionality reduction, clustering, cell-type annotation, differential expression, data integration, visualization and biological interpretation. - Good oral and written English skills are required, together with documented record of scientific publications. The following qualifications are highly desirable: - Experience with neuronal cell cultures, stem cell-derived neuronal populations, tumor innervation, synapses or neurobiology. - Experience with spatial molecular profiling, including spatial transcriptomics or proteomics, multiplexed imaging and/or integration of spatial transcriptomics with single-cell RNA-sequencing datasets. Experience from relevant research projects will be considered an advantage. Qualities of particular importance for the position: We are seeking an independent and structured researcher with the ability to plan, conduct, and complete complex research tasks. The applicant must demonstrate strong collaborative skills, an interest in supervising students, and a commitment to support an inclusive and productive research environment. Furthermore, the applicant must be able to combine practical laboratory work with quantitative data analysis. The applicant’s personal suitability for the position is a significant factor in the evaluation. ## We can offer: - Exciting development opportunities as part of your role in a strong professional environment - Salary NOK 690 000 (code 1352) in the state salary scale. For applicants with a degree in Medicine or Dentistry, salary NOK 700 000. For applicants with a medical specialization, salary NOK 725 000 (Applicants with specialist training must include a certificate of specialist approval from the Norwegian Directorate of Health). - Enrolment in the Norwegian Public Service Pension Fund - Good welfare benefits ## Your application must include: - A brief account of the applicant`s research interests and motivation for applying for the position - Transcripts and diplomas (applicants with education from other countries than Norway must enclose witnessed diplomas in both the original language and authorized translations) and documentation of submitted doctoral thesis - Complete list of publications - Publications (in PDF) it is important that each of the scholarly works on which the committee should place special emphasis, is attached in its entirety - Two references (name and contact information)
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