About the position
Scientist I - Assay Development & Screening
Ryvu Therapeutics
Kraków, Poland
We are looking for a Scientist I to join our Assay Development & Screening group, which builds and runs biochemical, biophysical and cell-based assays supporting Ryvu’s oncology discovery projects, from HTS to dose-response profiling.
KEY RESPONSIBILITIES
Independently plan and execute assay development, optimization and screening work packages aligned with project goals;
Develop and run plate-based assays (TR-FRET/HTRF, AlphaLISA, fluorescence, luminescence, ELISA), both biochemical and cell-based;
Characterize compound–target binding and kinetics (e.g., SPR, MST);
Run HTS and dose-response campaigns using automated liquid handling;
Design controls, analyze data (IC50/EC50, Z′), draw conclusions and propose next steps;
Author and standardize protocols and SOPs, and keep traceable records in ELN;
Present results, collaborate cross-functionally and with CROs, and train associate scientists.
YOUR BACKGROUND
MSc in biotechnology, biochemistry, molecular biology or a related field with ≥3 years of relevant experience, or a PhD with 0–1 year;
Hands-on assay development and/or HTS experience in pharma, biotech or a CRO;
Experience with lab automation and data analysis;
Ability to lead small work packages and present results clearly;
Basic use of approved AI tools, in line with SOPs and data protection rules;
English B2+.
Nice to have
SPR, MST, HCS, cell culture.
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Ryvu Therapeutics
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